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	Provedor de dados Arq. Bras. Med. Vet. Zootec. (1) BJMBR (1) BJPS (1) Autor Ferreira,A.J. (1) Gomes,M.G. (1) Gonçalves,G. (1) Kitten,G.T. (1) Ladeira,L.O. (1) Mandal,Snigdha Das (1) Mandal,Surjyanarayan (1) Martins-Júnior,P.A. (1) Melo,E.G. (1) Mendes,R.M. (1) Nunes,V.A. (1) Patel,Jayvadan (1) Resende,R.R. (1) Rezende,C.M.F. (1) Ribeiro,H.J. (1) Sousa,B.R. (1) Sá,M.A. (1) Valverde,T.M. (1) Mais... Palavra-chave Sodium hyaluronate (3) Box-Behnken design (1) Carbon nanotubes (1) Chondroitin sulfate (1) Curcumin/neuroprotective effect (1) Degenerative joint disease (1) Dog (1) Male mice C57BL/6 (1) NOR (1) Nanotechnology (1) Neurodegradation (1) Osseointegration (1) Osteoblast (1) Parkinson's disease/treatment (1) Response surface methodology (RSM) (1) Tissue engineering (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2017 (1) 2016 (1) 2008 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Effects of chondroitin sulfate and sodium hyaluronate on chondrocytes and extracellular matrix of articular cartilage in dogs with degenerative joint disease Arq. Bras. Med. Vet. Zootec. Gonçalves,G.; Melo,E.G.; Gomes,M.G.; Nunes,V.A.; Rezende,C.M.F.. Samples of articular cartilage of femur, tibia and patella of 15 dogs with experimentally induced degenerative joint disease (DJD) were microscopically analyzed. Animals were distributed into three groups (n=5): the control group received no medication; the second group was treated with chondroitin sulfate and the third received sodium hyaluronate. Samples were processed and stained with HE and toluidine blue for morphological evaluation. The metabolic and proliferative activity of the chondrocytes was evaluated by the measurement of nucleolar organizer regions (NORs) after impregnation by silver nitrate. Significant differences were not observed (P>0.05) in the morphology among the groups, however, the group treated with sodium hyaluronate had a higher... Tipo: Info:eu-repo/semantics/article Palavras-chave: Dog; Degenerative joint disease; Chondroitin sulfate; Sodium hyaluronate; NOR. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352008000100014 Intranasal mucoadhesivemicroemulsion for neuroprotective effect of curcuminin mptp induced Parkinson model BJPS Mandal,Snigdha Das; Mandal,Surjyanarayan; Patel,Jayvadan. ABSTRACT This study was to investigate the neuroprotective effect of curcumin against inflammation-mediated dopaminergic neurodegeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mice model of Parkinson's disease (PD). Curcumin loaded sodium hyaluronate based mucoadhesive microemulsion (CMME) was developed by using Box Behnken design of Response surface method (RSM) and was characterized. Male C57BL/6 mice were first treated with four intraperitoneal injections of MPTP (20 mg/kg of body weight) at 2 h intervals followed CMME intranasal administration for 14 days at 2.86 mg of curcumin/kg of body weight per once a day. Optimal CMME containing 3% Capmul MCM as oil phase, 37 % of Accenon CC and Transcutol HP at 2.5:1 ratio and 0.5% sodium... Tipo: Info:eu-repo/semantics/article Palavras-chave: Curcumin/neuroprotective effect; Response surface methodology (RSM); Box-Behnken design; Sodium hyaluronate; Neurodegradation; Parkinson's disease/treatment; Male mice C57BL/6. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200621 Single-walled carbon nanotubes functionalized with sodium hyaluronate enhance bone mineralization BJMBR Sá,M.A.; Ribeiro,H.J.; Valverde,T.M.; Sousa,B.R.; Martins-Júnior,P.A.; Mendes,R.M.; Ladeira,L.O.; Resende,R.R.; Kitten,G.T.; Ferreira,A.J.. The aim of this study was to evaluate the effects of sodium hyaluronate (HY), single-walled carbon nanotubes (SWCNTs) and HY-functionalized SWCNTs (HY-SWCNTs) on the behavior of primary osteoblasts, as well as to investigate the deposition of inorganic crystals on titanium surfaces coated with these biocomposites. Primary osteoblasts were obtained from the calvarial bones of male newborn Wistar rats (5 rats for each cell extraction). We assessed cell viability using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide assay and by double-staining with propidium iodide and Hoechst. We also assessed the formation of mineralized bone nodules by von Kossa staining, the mRNA expression of bone repair proteins, and the deposition of inorganic... Tipo: Info:eu-repo/semantics/article Palavras-chave: Osteoblast; Nanotechnology; Carbon nanotubes; Sodium hyaluronate; Tissue engineering; Osseointegration. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000200602 Registros recuperados: 3 Primeira ... 1 ... Última

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